human promyeloid leukemia hl60 (ATCC)
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Human Promyeloid Leukemia Hl60, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 7224 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 99 stars, based on 7224 article reviews
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1) Product Images from "Curcuminoids Activate TET Enzymes and Increase DNA Hydroxymethylation and Active Demethylation in Leukemia Cells"
Article Title: Curcuminoids Activate TET Enzymes and Increase DNA Hydroxymethylation and Active Demethylation in Leukemia Cells
Journal: International Journal of Molecular Sciences
doi: 10.3390/ijms27010310
Figure Legend Snippet: Curcuminoids increase global 5hmC in leukemia cells. Graded concentrations of curcumin (Cur) or DMC were used to treat U937 ( a , b ) and HL60 leukemia cells ( c , d ) for 48 h, followed by genomic DNA extraction and quantitation of global 5hmC as described in the methods. The data represent the mean of 3 replicates ± SD. * indicates a significant difference from the control at p < 0.05.
Techniques Used: DNA Extraction, Quantitation Assay, Control
Figure Legend Snippet: Curcuminoids increase TET enzymatic activity in leukemia cells. Graded concentrations of curcumin (Cur) or DMC were used to treat U937 ( a , b ) and HL60 leukemia cells ( c , d ) for 48 h, followed by nuclear protein extraction and quantitation of TET activity, as described in the methods. The data represent the mean of 3 replicates ± SD. * indicates significant difference from the control at p < 0.05.
Techniques Used: Activity Assay, Protein Extraction, Quantitation Assay, Control